The Egg Whisperer Show

I'm thrilled to bring you this conversation about a breakthrough in male fertility diagnostics that's been literally hiding in plain site. In this episode, I'm joined by Dr. Jeff Lysiak, PhD, co-founder and Chief Science Officer at PS Fertility, to discuss phosphatidylserine (PS) and how this critical molecule on sperm is revolutionizing how we diagnose male infertility. Jeff shares the fascinating story of how his research at the University of Virginia led to discovering that PS on the surface of sperm is essential for fertilization and how traditional semen analysis completely misses this vital piece of the puzzle.
Read the full show notes on my website. 
This episode addresses a frustration I've experienced for years in my practice: couples with "normal" semen analysis results who still have trouble when it comes to trying to conceive. Research shows that 20-30% of men with normal basic semen analysis could still be infertile, and we've had no way to identify them, until now. 

In this episode, we cover:

What phosphatidylserine (PS) is and why it's critical for sperm to fuse with and fertilize an egg
The major limitations of standard semen analysis (count, motility, morphology) and why 20-30% of men with "normal" results may still be infertile
How the PS Detect test works using flow cytometry to assess over 10,000 sperm per sample
The connection between varicocele and low PS scores—and how varicocelectomy surgery can restore PS levels to normal ranges
When the PS test should be ordered in a fertility workup and what to do if scores are low
Early data showing over 30% of men seeking fertility treatment have low PS scores, including those with normal semen analysis
How this test can prevent women from undergoing unnecessary treatments when the male factor is undiagnosed

Resources:

PS Fertility website: psfertility.com
PS Detect at-home test kit
Nature Communications publication on phosphatidylserine and fertilization
Dr. Aimee's Supplement Stack
The TUSHY Method
OVANAD+ by Theralogix. Use code EGG.
Would you like to learn more about IVF?
Click here to join Dr. Aimee for The IVF Class.
The next live class call is on Monday, April 20, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.
 
Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Other ways to connect:
Subscribe to my YouTube channel for more fertility tips
Join Egg Whisperer School
Subscribe to the newsletter to get updates
 
Keywords:
male infertility, phosphatidylserine, PS score, PS Detect, male fertility testing, semen analysis limitations, sperm function, fertilization competence, varicocele, unexplained infertility, IUI success rates, male factor infertility, reproductive urology, Jeff Lysiak, PS Fertility, sperm egg fusion, fertility diagnostics, at-home sperm test, idiopathic male infertility, fertility workup, egg whisperer show, Dr. Aimee

People seem to always be full of advice about fertility, and while most of it comes from a place of wanting to be helpful, not all of it is well informed or welcome. When you are trying to conceive, the last thing you want to hear is that you need to "relax." Or "go on a vacation, drink some wine, and let nature run its course." Am I right?
 
In this episode, I'm sharing the types of treatments that fertility doctors offer to patients, including information about fertility pills, fertility shots, IUI, and IVF. I'm also outlining some of the natural things you can do to improve your chances of conceiving, like salt floats, hypnotherapy, and self care.

Read the full show notes and transcript on Dr. Aimee's website

Would you like to learn more about IVF?
Click here to join Dr. Aimee for The IVF Class.
The next live class call is on Monday, April 20, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.
 
Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Other ways to connect:
Subscribe to my YouTube channel for more fertility tips
Join Egg Whisperer School
Subscribe to the newsletter to get updates

Did you know that fertility rates have dropped 50% in the last 5 decades, and more and more people are requiring help to grow their family? Some are calling it "Spermageddon." I'm not one to run with fantastical headlines, but the truth is that we are facing an infertility epidemic. And, this is all heartbreaking for the people dealing with infertility, and for us as a society.
 
Today, I'm honored to be joined by Dr. Shanna Swan on The Egg Whisperer Show to talk about this upsetting truth. Dr. Swan is one of the world's leading environmental and reproductive epidemiologists and a Professor of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai in New York City. An award-winning scientist, her work examines the impact of environmental exposures including chemicals such as phthalates and Bisphenol A, on men's and women's reproductive health and the neurodevelopment of children. She just recently published her book, "Countdown: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race."
 
We will be talking about the data and information that Dr. Swan has gathered, the environmental factors that are playing a role, and what we can do to reverse some of the impact. I hope you'll tune in and share this information far and wide. CountMeIn on changing this epidemic - and thank you for writing your eye-opening new book, Dr. Swan.
 
Read the full show notes on Dr. Aimee's website

Subscribe to my YouTube channel for more fertility tips!

Join Egg Whisperer School
Checkout the podcast
Subscribe to the newsletter to get updates

Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Hosted by Dr. Ban, I'm sharing everything you need to know about getting precision fertility care.... in ten minutes. You'll hear all about the TUSHY Method, the specifics of the BALLS Method, along with the Egg Whisperer DIET and your fertility TEAM.

There are many relatively easy and affordable ways to get smart about your fertility. We will never eliminate all of the unknowns, but we can take some simple steps to understand our body and how it may impact our ability to get pregnant.


For example, there are sperm kits that you can get delivered to your home without even needing to see a doctor. There's so much technology available now to improve treatment outcomes.


Yet, what I think is really important to note is that just because you see a fertility doctor it does not mean you want to do a treatment. I think that's a big barrier for people.


What I tell people is to go see someone and get your TUSHY checked, get your sperm checked. Learn more about yourself so that you're not wasting time or money doing something that's not going to work.

Read the full show notes on my website.

Do you have questions about IVF and Egg Freezing?
Join Dr. Aimee for The IVF Class, where you will learn all about IVF AND Egg Freezing, and have a chance to ask you her questions live on Zoom.
The next class call is on Monday, March 9, 2026 at 4pm PST (7pm EST).
You can enroll by clicking here.

Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Other ways to connect with Dr. Aimee and The Egg Whisperer Show:
Subscribe to my YouTube channel for more fertility tips!
Subscribe to the newsletter to get updates

I have patients that come to me from all over the world. There's one question I always ask when reviewing their IVF cycle history.


What was your embryo quality?


I hear time and time again from patients that they don't know it because their doctor told them embryo quality doesn't matter with IVF. That's simply not true!


Just like diamonds in a jewelry store. Quality matters. Just like there is a grading system for diamonds, there is also a grading system for embryos. It's important for you to know that this exists and to ask for your embryo grade.


When it comes to getting pregnant and IVF, the implantation rate is determined by the embryo quality and rating. 


Read the full show notes at Dr. Aimee's website.

Do you have questions about how embryo quality plays a role in IVF?
Dr. Aimee will answer your questions in The IVF Class.
The next live class call is on Monday, March 9, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.

Click to find The Egg Whisperer Show podcast on your favorite podcasting app.
 
Watch videos of Dr. Aimee answer Ask the Egg Whisperer Questions on YouTube.
 
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Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.