

Why Women Face Higher Alzheimer’s Risk (And The One Thing That Lowers It) | Dr Tommy Wood| Dr Tommy Wood
18/1/2026 | 7 min
Watch the FULL podcast here: https://youtu.be/QeNdkCVYquUAre women at higher risk of Alzheimer’s, and can life roles influence dementia risk? This clip explores why two-thirds of Alzheimer’s cases are in women, how vascular dementia differs, and how age-specific dementia risk has fallen over recent decades. We discuss factors like improved nutrition, better heart health care, and environmental complexity, jobs, education, and social engagement, linked to maintaining cognition into our 80s. A long-running study found lower environmental complexity, common among midcentury housewives, tracked with greater decline. We also touch on the importance of keeping the mind stimulated.***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/***Let’s be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

The Brain Has Bacteria? What the Brain Microbiome Means for Health and Longevity | William Li
16/1/2026 | 5 min
Watch the FULL podcast here: https://youtu.be/yZDzsfNjG_MCould your brain host healthy bacteria? This clip explores how parts once taught as sterile, such as breast milk, the bladder, and the brain, contain beneficial microbes, and what they might be doing. We touch on gut and brain communication through the vagus nerve, the idea of dysbiosis versus infection, and why modern findings ask for humility in medicine. Here, I’m discussing practical takeaways like paying attention to how your body feels and using biohacking to monitor health when tests fall short.***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days***Let’s be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

The Hardest Thing I’ve Learned About Self-Talk — and How to Stop Beating Yourself Up
14/1/2026 | 23 min
A quick note before we beginThis year, I’m doing something I’ve wanted to do for a long time.I want to start this year by sharing something a little different.After four years of Live Well Be Well, I’m introducing regular solo episodes. It’s taken me a long time to get here. Not because I didn’t have things to say, but because it’s taken a lot of belief in myself to sit here and share my own thoughts, reflections, and opinions, alongside the voices of the people I speak to on the show.These episodes aren’t about giving answers or telling you what to do. They’re about making sense of the patterns that keep showing up — in science, in health, and in ourselves.And I feel incredibly privileged to say that. I speak to some of the most respected, iconic people in this field a few times a week, and over the years, I’ve accumulated such a breadth of knowledge through those conversations. That breadth really matters when it comes to health, because nothing exists in isolation.These solo episodes are a way for me to distill all of that. To share what’s staying with me, what’s shaping the way I think, and what’s been on my mind each month.I also want this to feel like a conversation. Use the comments. Ask me questions. Tell me what you want to hear more about. These episodes, and this space, are where I want to respond.Love, Sarah Ann 💛***👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week. https://sarahmacklin.substack.com/This episode is sponsored by:NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at nowatch.com***The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days***Let’s be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe:http://www.youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/***If You Enjoyed This Episode, You Might Also Like:Neuroscientist’s 3 Proven Steps to Improve Brain Health & Prevent Cognitive Decline | Dr Tommy Woodhttps://youtu.be/QeNdkCVYquUThe Brain Immune Expert: ALERT! Social Media Is Reprogramming Your Immune System | Prof Nicolauhttps://youtu.be/2zNw6pzv8qk***Sign up to Sarah’s Compassionate Cure newsletter:Science Simplified, Health Humanised.Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact.https://sarahmacklin.substack.com/***Highlights Intro (00:00:00)Why Vulnerability Is the Real Starting Point (00:01:41)Brain vs Immune System: What Actually Came First (00:04:36)Negative Social Media Causes Inflammation (00:09:24)Burnout Permanently Changes Your Immune System (00:08:38)Dopamine Addiction, Phones, and Brain Overload (00:10:42)Why Boredom Is Essential for Brain Health (00:11:27)Fascia, Movement, and the Mind-Body Link (00:14:13)Emotional Granularity: A Hidden Health Tool (00:17:07)Redefining Success Through Mind-Body Health (00:19:58)What “Living Well, Being Well” Actually Means (00:20:58)Building a Health Community and Looking Ahead to 2026 (0:22:20)***Love what you’re hearing?My small ask is to please rate and review Live Well Be Well. This helps the show expand and allows me to keep producing these with the best quality guests. It means a huge amount to me, so thank you.

The Three S Model: Stimulus, Supply and Support for Cognitive Health and Dementia Risk | Dr Tommy Wood
12/1/2026 | 5 min
Watch the FULL podcast here: https://youtu.be/QeNdkCVYquUCan nutrition and supplements meaningfully lower dementia risk or mainly boost day-to-day focus? They matter within a broader Three S model that links stimulus, supply, and support for brain adaptation. This clip explores why cognitive challenge is the primary stimulus, how supply depends on blood flow, oxygen, and fuel, and how support includes sleep and less chronic stress. We discuss omega-3s, B vitamins, choline, vitamin D, magnesium, zinc, iron, and hydration, the heart-brain connection, and vascular dementia overlap, plus associations showing compounded risk from low D, poor omega-3 and B status, anemia, and homocysteine. ***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.👉 sarahannmacklin.com/vegoutReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.👉 sarahannmacklin.com/reset-your-health👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/***Let’s be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

Human Performance Scientist: Are GLP-1 weight loss drugs a solution or a risk? | Andy Galpin
09/1/2026 | 5 min
Are GLP-1 weight loss drugs a smart first step for obesity? They’re helping many people lose significant weight, yet concerns remain about side effects, muscle loss, cost, and regaining weight after stopping. This clip explores the promise and limits of GLP-1s, the call for long term data, and the need to pair medication with nutrition education, counseling, and strength training. It also considers real world access and whether short term success can translate into lasting health. ***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.👉 sarahannmacklin.com/vegoutReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.👉 sarahannmacklin.com/reset-your-health👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/***Let’s be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/



Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition