Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition

Exciting news - pre-order my debut book 
https://linktr.ee/HealthySBTH?utm_source=linktree_profile_shareYou've seen the headlines. You've watched the celebrities transform. Maybe you've even wondered, quietly, if it could be for you. But what is the science really saying?

This week on Live Well Be Well, I sit down with Dr. Jack Mosley, GP registrar, and author of Food Noise. Jack brings a perspective that is honest, nuanced, and completely free of hype. We get into what these drugs can genuinely do, who they are truly for, and why taking them without lifestyle support is like putting on noise-cancelling headphones without ever learning to listen to yourself.

Here's What We Dive Into:
- Why up to 40% of weight lost on GLP-1 medications can come from lean muscle, not fat, and why that matters more than the number on the scale.
- What "food noise" actually is and why silencing it with medication is only half the story.
- The 80% reality: why most people regain all their weight within 20 months of stopping and what the 20% who don't have in common.
- Why these are not cosmetic medications, who they are genuinely for, and the real risks of microdosing without clinical need.

Love,
Sarah Ann 💛
***

Want to put what Jack shared into practice? The Fast 800 combines intermittent fasting, nutrition, and guided lifestyle support in one place. Co-founded by his father Dr. Michael Mosley. Try it free for 7 days:
👉 www.thefast800.com

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This episode is sponsored by:
DIOME: Rest deeper. Stay grounded.
Rested is available now and Grounded lands later this month.
👉 Get 20% off with code SARAH20 at DIOME.CO

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The Great British Veg Out
How to support your gut, energy, and hormones by eating more — not less.
👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out
Reset Your Health
If your body feels off after stress, travel, or burnout — this is where to start.
👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days
👉 Practical beats perfect.
Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.
https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve
👉 If this resonates, you can join the thousands who read
The Compassionate Cure each week. https://sarahmacklin.substack.com/

***

Let’s be friends!
📷 Instagram: https://www.instagram.com/sarahannmacklin/
***

If You Enjoyed This Episode, You Might Also Like:
Fat Loss, Metabolism & The Myth Holding You Back | Dr Andy Galpin
https://youtu.be/ZXLWY5HcPXE
***

Sign up to Sarah’s Compassionate Cure newsletter:
Science Simplified, Health Humanised.
Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact.
https://sarahmacklin.substack.com/

***
Highlights
00:00:00 Intro00:01:45 The obesity crisis: how we got here and what's driving it
00:04:10 The string test: a simple way to assess your metabolic health
00:06:30 Muscle loss on GLP-1 medications and the stat no one is talking about
00:10:20 Benefits of GLP-1 drugs: heart disease, sleep apnea, and beyond
00:12:00 Food noise explained and how these drugs work like noise-cancelling headphones
00:15:00 GLP-1 and addiction: alcohol, opioids, and the reward system
00:20:30 Side effects, hair loss, and the dangers of unregulated sources
00:23:30 Microdosing Ozempic: what you really need to know
00:35:00 Shame spirals and the role of self-compassion in sustainable change
00:41:00 Managing cravings without medication: urge surfing and habit stacking
00:47:00 Weight regain after stopping: the 20-month reality check
00:50:30 The Mediterranean diet, the 5:2, and the Fast 800 programme
01:05:30 What live well, be well means to Dr. Jack Mosley

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Most women have heard of creatine — but only as something for gym bros loading up before a workout. What the sports science research actually shows is that creatine monohydrate may be one of the most important supplements for women navigating perimenopause, brain fog, gut issues, and mood changes — and almost no one is talking about it outside of performance circles. This clip breaks down exactly which form to take, how much, why it takes three weeks to work, and what the collagen supplement industry isn't telling you about protein intake and joint health.
Dr. Stacy Sims

Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠
Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com
Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell
***

Sign up to Sarah’s Compassionate Cure newsletter: 
Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://sarahmacklin.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Let’s be friends!
📷 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / sarahannmacklin⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
📹 Subscribe:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠   / @livewellbewellsarah  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
🐦 Twitter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / sarahannmacklin  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
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Most of us can list our values on demand — family, health, kindness — but do we actually live by them? This clip introduces the Saturday Test, a deceptively simple tool from relationship psychology: where you spend your free time and discretionary money on a Saturday reveals your true values far more accurately than anything you'd write in a journal. If you've ever wondered why your relationships keep hitting the same walls, or why you feel quietly out of alignment with your own life, this one question might be the most clarifying thing you do this week.
Listen to the full episode ⁠here⁠
Watch the full episode on Youtube ⁠here
***

This episode is sponsored by:
NOWATCH: The compassionate health tracker
Connecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/

Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell

***

The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.
👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.
👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days
👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes
👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

***

Let’s be friends!
📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah
🐦 Twitter: https://x.com/SarahAnnMacklin
📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

We're living in a $150 billion supplement industry, where every scroll through social media tells you you're missing something. A pill for your gut, your sleep, your hormones, your brain. It's exhausting. And more often than not, people are spending real money on things they can't fully explain, chasing solutions to problems they haven't properly diagnosed.

As a nutritionist, these are the questions I get asked about the most, so I wanted to sit down and give you my honest, evidence-based verdict on the supplements that are everywhere right now. Not hype. Not fear. Just clarity, so you can make decisions that are actually right for you.

Before we dive into the individual supplements, I want to give you a framework that I think changes everything. Before taking anything, ask yourself three questions: Why do I actually need this? How will I know if it's working? And could food solve this instead? These questions alone can save you a small fortune and a lot of confusion.

Here's What We Dive Into:
- Why most people are taking supplements without a clear reason, and the three questions that change everything.
- What creatine research is now revealing about women's brain health, mood, and aging.
- Why vitamin D is the one supplement that food genuinely cannot replace.
- How your gut microbiome actually thrives, and why a probiotic pill usually is not the answer.
- The honest truth about collagen, NAD+, and where your money is better spent.

Love,
Sarah Ann 💛

***

This episode is sponsored by:
NOWATCH: The compassionate health tracker
Connecting body and mind with unique stress recovery insights so you can live fully today
15% off with code LWBW15 at https://nowatch.com/ 

Mojo: the app for expert-led courses in better sex.
Learn from world-class sex therapists and relationship experts with courses tailored to your needs.
15% off with code LiveWell15 at mymojo.com/livewellbewell

***

The Great British Veg Out
How to support your gut, energy, and hormones by eating more — not less.
👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out
Reset Your Health
If your body feels off after stress, travel, or burnout — this is where to start.
👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days
👉 Practical beats perfect.
Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.
https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve
👉 If this resonates, you can join the thousands who read
The Compassionate Cure each week. https://sarahmacklin.substack.com/

***

Let’s be friends!
📷 Instagram: https://www.instagram.com/sarahannmacklin/
📹 Subscribe:http://www.youtube.com/@livewellbewellsarah

***
If You Enjoyed This Episode, You Might Also Like:
76% of People Don’t Get Enough Omega-3 - And It Affects Your Brain | Philip Calder
https://youtu.be/LkMKWzymU58

***

Sign up to Sarah’s Compassionate Cure newsletter:
Science Simplified, Health Humanised.
Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact.
https://sarahmacklin.substack.com/

***

00:00:00 Intro
00:00:31 The 3 questions to ask before any supplement
00:01:07 Magnesium: which form actually gets absorbed
00:04:25 Creatine for women: brain, mood, and aging
00:06:00 Creatine and depression: what the research found
00:08:10 Creatine in menopause: muscle, sleep, and strength
00:09:17 Omega-3: the label number that actually matters
00:11:30 Why today's salmon has less omega-3 than it used to
00:12:46 NAD+: hype or worth it?
00:15:04 Vitamin D: the one supplement food cannot replace
00:17:23 Probiotics: why your gut needs more than a capsule
00:19:40 Collagen: what the research actually says
00:22:00 Final verdict: what surprised me most

If you've ever felt like you're failing because you can't hold it together all the time — this conversation with philosopher and author Alain de Botton will change how you see yourself. Science confirms that happiness comes in 15-minute bursts, and the relentless pursuit of permanent calm is the very thing driving burnout in high-achieving women. You'll also discover the simple eight-minute text that could transform how you ask for help — and finally let the people who love you actually show up.
Alain De Button in conversation with Sarah Ann

Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

***

This episode is sponsored by:
NOWATCH: The compassionate health tracker
Connecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/

Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell

***

The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.
👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.
👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days
👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes
👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

***

Let’s be friends!
📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah
🐦 Twitter: https://x.com/SarahAnnMacklin
📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/