Ageless and Timeless Podcast®

What can the microbes in our gut tell us about health—and how much do we still have to learn? On Ageless & Timeless, Michele Hughes welcomes gastroenterologist and microbiome researcher Dr. Sabine Hazan to discuss the science of the gut and why she believes care should begin with the individual.

Dr. Hazan shares how treating patients with Crohn’s disease and conducting clinical trials led her to study the microbiome. She explains why medical history, diet, environment, and response to treatment matter when interpreting findings. They also discuss fecal microbiota transplantation, the challenge of finding suitable donors, and why promising observations need larger studies. Dr. Hazan reflects on breaking barriers as the first woman gastroenterology fellow at the University of Florida and on the importance of questioning conclusions in medicine.

Medical Disclaimer – Ageless and Timeless Podcast

Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

What if aging is inevitable—but deterioration is negotiable? In this episode of the Ageless & Timeless Podcast, host Michele Hughes welcomes longtime friend, former Mr. America, and performance and longevity strategist Tom Terwilliger for a powerful conversation about reinvention, sustainable achievement, and remaining strong throughout the entire performance curve of life. Tom shares his remarkable journey from struggling with dyslexia and hyperactivity as a child to riding with outlaw bikers—and the life-changing moment that compelled him to walk away. He explains how bodybuilding gave him a new direction, eventually leading him to win the 1986 Mr. America title. But reaching the top did not silence the old beliefs that had driven him. Tom reveals how his understanding of success evolved from force-based living—pushing through stress, fear, and feelings of inadequacy—to a mastery-based approach built around self-awareness, recovery, resilience, and purpose. Michele and Tom also explore the foundational pillars of healthy aging, including nutrition, strength training, movement, sleep, stress regulation, mindset, relationships, and purpose. Tom explains why resilience is not simply about how much pressure you can withstand, but how effectively your nervous system can recover and return to baseline. This candid and inspiring conversation reminds us that longevity is not about trying to become who you were decades ago. It is about becoming the strongest, healthiest, and most capable version of yourself at the age you are today. Special Offer: Get immediate access to Performance Curve for just $1 and experience it for 14 days. Read it, follow the thinking, try what makes sense, and decide whether it belongs in your life. Visit GetPerformanceCurve.com to learn more.

Medical Disclaimer: The information presented on the Ageless & Timeless Podcast is provided for educational and informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your physician or another qualified healthcare provider before beginning a new exercise, nutrition, supplement, or wellness program. Never disregard professional medical advice or delay seeking it because of something discussed on this podcast. The views and opinions expressed by guests are their own and do not necessarily reflect those of the host or the podcast.

What does it truly mean to live longer—and how can we separate promising longevity science from exaggerated claims? In this episode of the Ageless and Timeless Podcast, Michele Hughes welcomes back longevity researcher and biogerontology scientist Bill Lawrence, PhD, for an evidence-focused exploration of biological aging, healthspan, and peptide bioregulators. Dr. Lawrence explains the important distinctions between lifespan, healthspan, and biological longevity. He also discusses how researchers use biomarkers such as telomere length, epigenetic testing, pace of aging, and organ-specific biological age to evaluate potential longevity interventions. Drawing upon his work with the scientific legacy of Professor Vladimir Khavinson, Dr. Lawrence introduces Khavinson Peptide Bioregulators—short, organ-specific regulatory peptides studied for their potential influence on gene expression, cellular repair, and age-related functional decline. He explains how these compounds differ from popular synthetic peptides and why the two categories may serve very different purposes. The conversation also examines the evidence behind today’s most talked-about longevity interventions. Dr. Lawrence separates approaches that may improve general health or reduce disease risk from those he believes meet a more rigorous standard for influencing biological aging. Michele and Dr. Lawrence DiscussThe difference between lifespan, healthspan, and biological longevity
Why Americans may spend so many of their later years managing chronic illness
The importance of published research and measurable biomarkers
How telomeres and epigenetic clocks are used to estimate biological aging
How organ-specific biological age testing can help identify accelerated aging
The difference between peptide bioregulators and synthetic therapeutic peptides
Why synthetic peptides may be better suited to short-term or acute needs
The long-term, regenerative focus of peptide bioregulators
Professor Vladimir Khavinson’s research into pineal and thymus peptides
The Hayflick limit and the role of cellular replication in aging
Research examining peptides, mortality risk, and age-related functional decline
Studies involving peptide bioregulators and vision-related conditions
How personalized peptide protocols may be developed using biological-age testing
Dr. Lawrence’s ongoing biological-age interventional studies
This episode is the first part of an expansive discussion with Dr. Lawrence. A future conversation will continue with peptide bioregulators, biological-age reversal, and the measurable outcomes emerging from his research. About Bill Lawrence, PhD Bill Lawrence, PhD, is a longevity researcher and biogerontology scientist specializing in Khavinson Peptide Bioregulators, biological aging, and epigenetic regulation. His work focuses on translating decades of Eastern European and Russian research involving short regulatory peptides into frameworks accessible to Western clinicians and researchers. Dr. Lawrence is closely associated with the scientific legacy of Vladimir Khavinson, MD, PhD, whose laboratory and clinical studies investigated organ-specific peptide bioregulators and their potential roles in gene expression, tissue repair, and age-related functional decline. Dr. Lawrence’s work centers on mechanistic interpretation, clinical synthesis, and biomarker-based evaluation, particularly through epigenetic aging measurements, telomere biology, and systems-level biomarkers. He currently administers two biological-age interventional clinical studies. Medical Disclaimer – Ageless and Timeless Podcast Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment. While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

Please note: This episode includes discussion of vaccines, public-health policy, medical research, pharmaceutical interventions, and political figures. The views and claims expressed by the guest are his own and do not necessarily reflect those of the Ageless and Timeless Podcast®, its host, producers, or affiliated organizations. This episode is presented for discussion purposes and is not a substitute for professional medical advice or guidance from qualified public-health authorities.

In this episode of the Ageless and Timeless Podcast®, host Michele Hughes welcomes Del Bigtree, filmmaker, host of The HighWire, and former communications director for Robert F. Kennedy Jr.’s presidential campaign.

Del discusses the response to his documentary, An Inconvenient Study, and the experiences that led him from working as a producer on the CBS daytime show The Doctors to independent filmmaking and media.

The conversation offers a more personal look at the upbringing, faith, optimism, and sense of purpose that have influenced his life and career. Del shares his belief that small, consistent actions can contribute to larger outcomes, even when the complete path forward is not immediately clear.

Del also discusses his personal approach to longevity and well-being. He shares how meditation helps him slow down and evaluate decisions, as well as the roles movement, hydration, intermittent fasting, sauna use, food choices, and time with family play in his daily life.

He and Michele also discuss recognizing negative thought patterns, developing a more constructive internal dialogue, and becoming more present during everyday activities. This wide-ranging conversation explores the personal experiences, routines, and beliefs that have shaped Del’s career and approach to life. 

Medical Disclaimer – Ageless and Timeless Podcast Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

What if skincare could do more than temporarily improve the surface of your skin? In this episode of the Ageless and Timeless Podcast host Michele Hughes welcomes husband-and-wife entrepreneurs Natalie Novak and Ron Webb, founders of KPS— Kindness Powered Skincare. Together, they share how Natalie’s background as an organic farmer and Ron’s experience in aerospace engineering, plant research, and animal wound care inspired an unconventional approach to skin health. Natalie and Ron explain how KPS creates its own proprietary botanical extracts in itsn Michigan laboratory, combining clean, carefully selected ingredients with a scientific focus on bioavailability and efficacy. They discuss their belief that the skin reflects what is happening throughout the body and explore the connections among skin health, cellular signaling, hydration, collagen production, the microbiome, fascia, lymphatic flow, inflammation, and the nervous system. The conversation also explores KPS’s Renew Body Sculptor and the company’s approach to relaxing fascia, supporting lymphatic movement, improving the appearance of cellulite, and helping the body move from a state of stress toward relaxation. Natalie and Ron discuss how their products are being incorporated into spas and medical practices, including protocols designed to support people experiencing acne, rosacea, eczema, skin laxity, chronic discomfort, and changes associated with significant weight loss. Natalie shares KPS’s recommended at-home skincare routine, beginning with its triple cleansing method and progressing through nourishment and targeted treatment. For anyone wanting to begin with just one product, the founders recommend the signature Renew Face Cream. Throughout the episode, Natalie and Ron emphasize that healthy aging requires more than skincare alone. Nutrition, exercise, sleep, stress management, detoxification, and other foundational lifestyle practices all contribute to healthier, more resilient skin. The couple also shares the heart behind KPS: a commitment to giving back, supporting women undergoing oncology treatments, and ultimately making advanced skincare and wellness solutions more accessible to people who may not otherwise be able to afford them. In This Episode ● How an organic farmer and aerospace engineer created KPS ● Why the skin can provide clues about internal health ● The role of botanical nutrients and cellular signaling in skincare ● How fascia may affect lymphatic flow, discomfort, and skin appearance ● The connection between the skin microbiome and conditions such as acne and rosacea ● Supporting collagen, hydration, volume, and elasticity ● Skincare considerations following weight loss or GLP-1 use ● The KPS triple-cleansing and at-home treatment protocol ● Why healthy skin begins with whole-body health ● Natalie and Ron’s mission to make advanced skincare more accessible Special Offer for Ageless and Timeless Listeners Receive 20% off your KPS Essentials purchase with code AGELESS20 at checkout. Shop using this special link: www.kpsessentials.com/discount/AGELESS20 KPS also offers a 60-day money-back guarantee. Medical professionals, aestheticians, spas, pharmacists, and other qualified professionals can find wholesale information through the KPS website. The information shared in this episode is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any medical condition. Product experiences and results may vary. Medical Disclaimer – Ageless and Timeless Podcast Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment. While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.