Ageless and Timeless Podcast®

What does it truly mean to live longer—and how can we separate promising longevity science from exaggerated claims? In this episode of the Ageless and Timeless Podcast, Michele Hughes welcomes back longevity researcher and biogerontology scientist Bill Lawrence, PhD, for an evidence-focused exploration of biological aging, healthspan, and peptide bioregulators. Dr. Lawrence explains the important distinctions between lifespan, healthspan, and biological longevity. He also discusses how researchers use biomarkers such as telomere length, epigenetic testing, pace of aging, and organ-specific biological age to evaluate potential longevity interventions. Drawing upon his work with the scientific legacy of Professor Vladimir Khavinson, Dr. Lawrence introduces Khavinson Peptide Bioregulators—short, organ-specific regulatory peptides studied for their potential influence on gene expression, cellular repair, and age-related functional decline. He explains how these compounds differ from popular synthetic peptides and why the two categories may serve very different purposes. The conversation also examines the evidence behind today’s most talked-about longevity interventions. Dr. Lawrence separates approaches that may improve general health or reduce disease risk from those he believes meet a more rigorous standard for influencing biological aging. Michele and Dr. Lawrence DiscussThe difference between lifespan, healthspan, and biological longevity
Why Americans may spend so many of their later years managing chronic illness
The importance of published research and measurable biomarkers
How telomeres and epigenetic clocks are used to estimate biological aging
How organ-specific biological age testing can help identify accelerated aging
The difference between peptide bioregulators and synthetic therapeutic peptides
Why synthetic peptides may be better suited to short-term or acute needs
The long-term, regenerative focus of peptide bioregulators
Professor Vladimir Khavinson’s research into pineal and thymus peptides
The Hayflick limit and the role of cellular replication in aging
Research examining peptides, mortality risk, and age-related functional decline
Studies involving peptide bioregulators and vision-related conditions
How personalized peptide protocols may be developed using biological-age testing
Dr. Lawrence’s ongoing biological-age interventional studies
This episode is the first part of an expansive discussion with Dr. Lawrence. A future conversation will continue with peptide bioregulators, biological-age reversal, and the measurable outcomes emerging from his research. About Bill Lawrence, PhD Bill Lawrence, PhD, is a longevity researcher and biogerontology scientist specializing in Khavinson Peptide Bioregulators, biological aging, and epigenetic regulation. His work focuses on translating decades of Eastern European and Russian research involving short regulatory peptides into frameworks accessible to Western clinicians and researchers. Dr. Lawrence is closely associated with the scientific legacy of Vladimir Khavinson, MD, PhD, whose laboratory and clinical studies investigated organ-specific peptide bioregulators and their potential roles in gene expression, tissue repair, and age-related functional decline. Dr. Lawrence’s work centers on mechanistic interpretation, clinical synthesis, and biomarker-based evaluation, particularly through epigenetic aging measurements, telomere biology, and systems-level biomarkers. He currently administers two biological-age interventional clinical studies. Medical Disclaimer – Ageless and Timeless Podcast Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment. While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

Please note: This episode includes discussion of vaccines, public-health policy, medical research, pharmaceutical interventions, and political figures. The views and claims expressed by the guest are his own and do not necessarily reflect those of the Ageless and Timeless Podcast®, its host, producers, or affiliated organizations. This episode is presented for discussion purposes and is not a substitute for professional medical advice or guidance from qualified public-health authorities.

In this episode of the Ageless and Timeless Podcast®, host Michele Hughes welcomes Del Bigtree, filmmaker, host of The HighWire, and former communications director for Robert F. Kennedy Jr.’s presidential campaign.

Del discusses the response to his documentary, An Inconvenient Study, and the experiences that led him from working as a producer on the CBS daytime show The Doctors to independent filmmaking and media.

The conversation offers a more personal look at the upbringing, faith, optimism, and sense of purpose that have influenced his life and career. Del shares his belief that small, consistent actions can contribute to larger outcomes, even when the complete path forward is not immediately clear.

Del also discusses his personal approach to longevity and well-being. He shares how meditation helps him slow down and evaluate decisions, as well as the roles movement, hydration, intermittent fasting, sauna use, food choices, and time with family play in his daily life.

He and Michele also discuss recognizing negative thought patterns, developing a more constructive internal dialogue, and becoming more present during everyday activities. This wide-ranging conversation explores the personal experiences, routines, and beliefs that have shaped Del’s career and approach to life. 

Medical Disclaimer – Ageless and Timeless Podcast Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

What if skincare could do more than temporarily improve the surface of your skin? In this episode of the Ageless and Timeless Podcast host Michele Hughes welcomes husband-and-wife entrepreneurs Natalie Novak and Ron Webb, founders of KPS— Kindness Powered Skincare. Together, they share how Natalie’s background as an organic farmer and Ron’s experience in aerospace engineering, plant research, and animal wound care inspired an unconventional approach to skin health. Natalie and Ron explain how KPS creates its own proprietary botanical extracts in itsn Michigan laboratory, combining clean, carefully selected ingredients with a scientific focus on bioavailability and efficacy. They discuss their belief that the skin reflects what is happening throughout the body and explore the connections among skin health, cellular signaling, hydration, collagen production, the microbiome, fascia, lymphatic flow, inflammation, and the nervous system. The conversation also explores KPS’s Renew Body Sculptor and the company’s approach to relaxing fascia, supporting lymphatic movement, improving the appearance of cellulite, and helping the body move from a state of stress toward relaxation. Natalie and Ron discuss how their products are being incorporated into spas and medical practices, including protocols designed to support people experiencing acne, rosacea, eczema, skin laxity, chronic discomfort, and changes associated with significant weight loss. Natalie shares KPS’s recommended at-home skincare routine, beginning with its triple cleansing method and progressing through nourishment and targeted treatment. For anyone wanting to begin with just one product, the founders recommend the signature Renew Face Cream. Throughout the episode, Natalie and Ron emphasize that healthy aging requires more than skincare alone. Nutrition, exercise, sleep, stress management, detoxification, and other foundational lifestyle practices all contribute to healthier, more resilient skin. The couple also shares the heart behind KPS: a commitment to giving back, supporting women undergoing oncology treatments, and ultimately making advanced skincare and wellness solutions more accessible to people who may not otherwise be able to afford them. In This Episode ● How an organic farmer and aerospace engineer created KPS ● Why the skin can provide clues about internal health ● The role of botanical nutrients and cellular signaling in skincare ● How fascia may affect lymphatic flow, discomfort, and skin appearance ● The connection between the skin microbiome and conditions such as acne and rosacea ● Supporting collagen, hydration, volume, and elasticity ● Skincare considerations following weight loss or GLP-1 use ● The KPS triple-cleansing and at-home treatment protocol ● Why healthy skin begins with whole-body health ● Natalie and Ron’s mission to make advanced skincare more accessible Special Offer for Ageless and Timeless Listeners Receive 20% off your KPS Essentials purchase with code AGELESS20 at checkout. Shop using this special link: www.kpsessentials.com/discount/AGELESS20 KPS also offers a 60-day money-back guarantee. Medical professionals, aestheticians, spas, pharmacists, and other qualified professionals can find wholesale information through the KPS website. The information shared in this episode is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any medical condition. Product experiences and results may vary. Medical Disclaimer – Ageless and Timeless Podcast Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment. While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

What if the answers to many of your health challenges were already written in your DNA?

In this episode of the Ageless and Timeless Podcast®, Michele Hughes welcomes Kim Ressler, Founder and CEO of SNiP Nutrigenomics, for a fascinating conversation about the future of personalized health. After spending more than a decade searching for solutions to her own health struggles, Kim discovered the power of nutrigenomics—the science of understanding how your genes influence your nutritional needs—and has since dedicated her career to helping others optimize their health through personalized wellness strategies.

Kim explains how genetic testing can reveal important insights about detoxification pathways, vitamin absorption, inflammation, cardiovascular health, methylation, and more. Rather than treating symptoms, nutrigenomics focuses on identifying the body's unique needs and creating targeted nutritional support based on an individual's genetic blueprint.

Michele and Kim also explore the powerful role that mindset, lifestyle habits, community, gratitude, and purpose play in healthy aging. Together, they discuss why your genes are not your destiny and how understanding your biology can empower you to make better decisions that support both lifespan and healthspan.

Medical Disclaimer – Ageless and Timeless Podcast Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

On this episode of the Ageless and Timeless Podcast®, host Michele Hughes sits down with Dominika Laureto for an inspiring and deeply informative conversation about modern wellness, regenerative medicine, aesthetics, and the future of personalized healthcare.

From immigrating to the United States from Poland without speaking English to becoming a highly respected trauma nurse specialist and successful wellness entrepreneur, Dominika’s story is a true example of resilience, integrity, and the American dream.

Dominika shares her journey through emergency medicine, explaining how years spent working in high-pressure ER environments exposed the limitations of conventional symptom-based healthcare. Frustrated by a system focused on managing disease rather than preventing it, she sought a more proactive and comprehensive approach to wellness. This path led her into aesthetic medicine, functional medicine, regenerative therapies, and ultimately to creating a thriving practice that blends internal health optimization with external rejuvenation.

Topics discussed include:
Root-cause medicine
Comprehensive blood work
Hormone optimization
Inflammation management
Peptides and regenerative therapies
GLP-1 medications for weight management and longevity
Body recomposition versus simple weight loss
Muscle preservation and resistance training
Personalized treatment protocols
The discussion also explores aesthetic treatments and technologies including:
Microneedling
Laser therapies
Sculptra
Collagen stimulation
Skin laxity treatments
Peptide therapies such as GHK-CU and BPC-157

The impact of internal inflammation on aesthetic outcomes Dominika also discusses her upcoming book, Awaken, which focuses on functional wellness, aesthetics, and foundational health optimization strategies.

Medical Disclaimer

Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content should not be used as a substitute for professional medical advice, diagnosis, or treatment.

Listeners are encouraged to consult with licensed medical professionals before making health-related decisions. By listening to the podcast, listeners acknowledge that any actions taken based on the information presented are at their own risk, and neither the show, its host, guests, nor affiliates are liable for damages resulting from the use of the content.