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The Journal of Clinical Psychiatry Podcast

The JCP Podcast
The Journal of Clinical Psychiatry Podcast
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  • From Academia to Industry: Dr. Stephen Brannan’s Journey in Shaping Modern Mental Health Care
    Dr. Stephen Brannan brings decades of experience from both academic psychiatry and leadership roles at top pharmaceutical companies to the JCP Podcast today. He details his transition from university research to industry, offering a candid look at the forces that drive innovation in mental health care. Dr. Brannan unpacks the complex process of bringing a new drug to market, using his work on treatments like Cobenfy (xanomeline-trospium) as a case study. The discussion covers the critical decisions in clinical trial design, from selecting the right patient populations to establishing meaningful endpoints that satisfy both regulatory bodies and clinical needs. He also addresses some of the most persistent hurdles in psychiatric research including the high placebo response rates that can obscure a drug's true efficacy and the operational complexities of running large, multinational studies. For clinicians seeking to better understand the evidence behind new medications, Dr. Brannan’s insights provide a unique level of enlightenment in the pragmatism, science, and collaboration required to advance patient care.Episode Highlights:00:00 - Introducing Dr. Stephen Brannan01:56 - From Pre-Med Doubts to a Career in Psychiatry06:51 - The "Push and Pull" from Academia to Industry08:50 - Advice for Young Psychiatrists Considering Industry10:56 - Pitfalls and Misconceptions of Pharmaceutical Work14:37 - Balancing Real-World Applicability and Regulatory Realities20:40 - The Science and Strategy Behind Cobenfy22:10 - Understanding and Mitigating the Placebo Effect28:57 - The Role of Expert Steering Committees32:38 - Designing Trials42:37 - The Nuances of Safety Surveillance in Clinical Trials53:27 - Reflections on the Future of Psychiatric TreatmentKey Takeaways:"I will not sacrifice quality for the sake of speed.""I've learned how to talk with people rather than just sort of barking an order.""We're a hell of a lot more alike than we're different.""The better we understand that and we're able to pick treatments based on biomarkers...that's going to make a huge impact.""That's extremely useful in psychiatry because it's rare when you first see somebody...you absolutely know what's going on. It usually takes time and patience and a tolerance for ambiguity.""You also want to be able to talk to people who will tell you what's wrong with your thinking.""You want your beachhead. And your beachhead is...what's the best segment of patients?"Links: Full transcript and show notes: https://www.psychiatrist.com/jcp/ep3-academia-to-pharma-stephen-brannanJournal of Clinical Psychiatry: psychiatrist.com/jcp/ Dr. Stephen Brannan: https://www.linkedin.com/in/steve-brannan-b7376019/
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  • Leadership in Clinical Psychopharmacology with Joseph Goldberg, MD
    Dr. Joseph Goldberg, Clinical Professor at the Icahn School of Medicine at Mount Sinai and immediate past president of the American Society of Clinical Psychopharmacology (ASCP), shares insights from his remarkable career, from his beginnings in neuroscience to his influential leadership roles. Along the way, he explores the future of mental health, focusing on mentorship, innovative education, and translating research into patient-centered care.Throughout the episode, Dr. Goldberg recounts his unique journey into psychiatry, which began with studying frogs and led to a focus on bipolar disorder. He offers an insider’s view of the ASCP, detailing initiatives from his presidency, including task forces on ketamine and de-prescribing. A key highlight is ASCP’s revolutionary AI-enhanced "living textbook," a new approach to medical education designed to transform how clinicians learn about psychopharmacology, ensuring the latest knowledge is always accessible.Episode Highlights:00:00 - Introducing Dr. Joseph Goldberg, MD01:13 - From Frogs to Psychiatry: A Scientist’s Origin Story02:51 - Why Bipolar Became the Focus: Early Pharmacology Momentum04:20 - ASCP’s Patient-Centered Mission & Why It Became “Home”05:08 - Mentorship Pipeline: NCDEU Roots and Career Breaks08:10 - Leadership Model in Action & New President Anita Clayton11:17 - ASCP Task Forces: Ketamine/Esketamine and Deprescribing Guidance14:13 - CME 2.0 & AI “Living Textbook” (edYOU) for Psychopharm Education18:43 - Limbic Learning & Nasrallah Award: Make Education Stick20:18 - Early-Career Lift: Posters, Committees, New Investigator Awards23:18 - What’s Next in Psychopharm: Tangible Advances for Patients25:44 - ASCP × JCP Synergy & Membership Call to Action27:40 - Looking Ahead: Bridging Bench to Bedside with Future GuestsKey Takeaways:"The frogs brought me to med school, brought me to research in psychiatry and psychopharmacology, and, well, here I am today.""ASCP has always been my professional home, intellectually, scientifically, even socially.""It's really about the pragmatic translation of findings into clinical care, which just really spoke to my interest in the kind of 'so what' factor of what it is we do.""It's a living textbook in psychopharmacology, so it can be continually updated. We hope it's going to revolutionize the way we teach psychopharmacology.""Steve and I both call this 'limbic learning.' You remember things when they're presented in an impactful kind of way. It's almost like PTSD in reverse.""We live in a time and an era of true advances. We have things in our pharmacopeia now that did not exist 5 years ago.""This is a home. This is a place where I think you will find like-minded people. You'll make friends for life.""If you interact with ASCP or JCP, you will not ask the question, 'What does this have to do with my patients?'"Links: Full transcript and show notes: https://www.psychiatrist.com/jcp/ep2-clinical-psychopharmacology-joe-goldberg/ Journal of Clinical Psychiatry: psychiatrist.com/jcp/ Dr. Joseph Goldberg, MD: https://www.josephgoldbergmd.com/American Society of Clinical Psychopharmacology: https://ascpp.org/
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  • The Mission of JCP with Editor-in-Chief Marlene P. Freeman, MD
    In its inaugural episode, the JCP Podcast features a foundational conversation with Dr. Marlene Freeman, Editor-in-Chief of The Journal of Clinical Psychiatry, in which she discusses the journal's core mission to empower busy mental health professionals with cutting-edge, evidence-based research. Providing insights into academic publishing, from the peer review process to the journal's vision for psychiatric education, today’s discussion offers essential listening for those at the intersection of clinical practice and scientific discovery.Dr. Freeman details her professional journey into women's mental health and perinatal psychiatry, and goes on to explore how the journal balances scientific rigor with clinical relevance to support shared decision-making in patient care. Navigating the complex publication landscape, the episode addresses industry-sponsored studies, the importance of diverse voices, and emerging trends like digital therapeutics, biomarkers, and the potential impact of artificial intelligence on psychiatric research. Episode Highlights:00:00 - JCP Podcast Mission for Busy Clinicians00:37 - Introducing Dr. Marlene Freeman, Editor-in-Chief02:36 - Choosing Psychiatry for Patient-Centered Impact04:19 - JCP’s Purpose: Clinician-Ready, Evidence-Based Guidance08:03 - Faster Access to Research: Summaries, Email TOCs, Podcasts, Specialty Sections11:33 - Shared Decision-Making in Practice & ASCP Corner Quick Reviews15:11 - What JCP Publishes & How Peer Review Ensures Clinical Quality25:11 - Promoting Diversity, Inclusion, and Ethical Publication Standards27:00 - Emerging Priorities: Novel Treatments, TRD, and Real-World Effectiveness30:24 - Digital Therapeutics & Biomarkers Must Prove Clinical Utility36:02 - AI in Publishing: Verify References and Read Full Papers40:00 - Clinician-First Perspective: Practice Informs Editing & Research42:03 - Editorial Impact and Evolving Ethical Responsibilities45:18 - Reflections on Leadership, Legacy, and Lifelong LearningKey Takeaways:"I really want to emphasize that a rejection of a paper doesn't mean it isn't high quality.""We want to be user-friendly to authors. We want to save them time. So if we're not a good fit for their paper, I'm very comfortable looking at whatever people want to send me in advance.""We want to make sure that we're making collaborative decisions with patients, but we have to make sure that we're offering good choices.""The work could not be done without peer reviewers.""You get so much out of reading the full paper. The introduction section is like a mini review of that topic and gives you so much more information.""We want to make sure that what we're putting out there is not a result of the financial investment that a company has made. We want it to be based purely on the research and what it has to add for patients.""We want to make sure that we are providing treatments that everyone can access.""I think that all the roles inform each other, but at the heart of it, I'm a clinician."Links: Full transcript and show notes: psychiatrist.com/jcp/ep1-mission-jcp-marlene-freeman Journal of Clinical Psychiatry: psychiatrist.com/jcp/ Interested in becoming a peer reviewer? psychiatrist.com/jcp/reviewers/
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  • Trailer
    The Journal of Clinical Psychiatry Podcast explores the science, practice, and human side of mental health care. Hosted by Dr. Ben Everett, Senior Scientific Director at Physicians Postgraduate Press, the series brings together leading voices in psychiatry, neuroscience, and behavioral medicine to discuss the evidence shaping clinical care today. Each episode features thoughtful conversations with JCP authors, academic experts, and frontline clinicians exploring disorders across the mental health continuum, from schizophrenia and mood disorders to anxiety, depression, and sleep-related conditions. By bridging research and real-world practice, the podcast delivers insights that empower psychiatrists, nurse practitioners, physician associates, and primary care clinicians to deliver better care for patients with mental illness. Insightful. Evidence-based. Human-centered.
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The Journal of Clinical Psychiatry Podcast explores the science, practice, and human side of mental health care. Hosted by Dr. Ben Everett, Senior Scientific Director at Physicians Postgraduate Press, the series brings together leading voices in psychiatry, neuroscience, and behavioral medicine to discuss the evidence shaping clinical care today. Each episode features thoughtful conversations with JCP authors, academic experts, and frontline clinicians exploring disorders across the mental health continuum, from schizophrenia and mood disorders to anxiety, depression, and sleep-related conditions. By bridging research and real-world practice, the podcast delivers insights that empower psychiatrists, nurse practitioners, physician associates, and primary care clinicians to deliver better care for patients with mental illness. Insightful. Evidence-based. Human-centered.
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