Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald speaks with Tom Fabian, PhD, Senior Educator and Research Specialist at Diagnostic Solutions Laboratory, about why higher protein intake doesn’t always lead to better muscle outcomes. Emerging research shows that digestion, microbiome balance, and immune signaling all influence how effectively the body utilizes dietary protein.

Dr. Fabian explores the gut–muscle axis and explains how microbiome-derived metabolites and regulatory T cells support tissue repair and recovery. The conversation also highlights why variability in protein digestion matters and how evaluating gut function can help practitioners determine whether patients are positioned to benefit from higher protein intake.

Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

GUEST DETAILS

Tom Fabian, PhD, translates microbiome research into clinical insights for functional medicine. He is a science advisor with Diagnostic Solutions Laboratory and a Science Advisory Board member with Designs for Health.

Email: [email protected]

THANKS TO OUR SPONSOR

Diagnostic Solutions Laboratory
Phone: 877-485-5336

Explore DSL’s advanced clinical testing and create your practitioner account at http://diagnosticsolutionslab.com/fxmedpodcast

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In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald speaks with Tom Fabian, PhD, Senior Educator and Research Specialist at Diagnostic Solutions Laboratory, about why higher protein intake doesn’t always lead to better muscle outcomes. Emerging research shows that digestion, microbiome balance, and immune signaling all influence how effectively the body utilizes dietary protein.

Dr. Fabian explores the gut–muscle axis and explains how microbiome-derived metabolites and regulatory T cells support tissue repair and recovery. The conversation also highlights why variability in protein digestion matters and how evaluating gut function can help practitioners determine whether patients are positioned to benefit from higher protein intake.

Transcript, show notes, and a free Clinical Takeaways handout for a concise summary of key insights from this episode at https://www.drkarafitzgerald.com/fxmed-podcast/

GUEST DETAILS

Tom Fabian, PhD, translates microbiome research into clinical insights for functional medicine. He is a science advisor with Diagnostic Solutions Laboratory and a Science Advisory Board member with Designs for Health.

THANKS TO OUR SPONSOR

Diagnostic Solutions
Phone: 877-485-5336

Explore DSL’s advanced clinical testing and create your practitioner account at http://diagnosticsolutionslab.com/fxmedpodcast

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

As more patients present with digestive sensitivity and increasingly restricted diets, restoring gut resilience has become a central clinical challenge. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald speaks with Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, about emerging microbiome science and practical strategies for supporting microbial balance, dietary tolerance, and metabolic health.

The discussion explores next-generation probiotic strains, fiber diversity, IBS patterns, and real-world approaches clinicians can use to help patients rebuild microbiome resilience and expand diet diversity in practice.

Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

GUEST DETAILS

Colleen Cutcliffe, PhD, is CEO and Co-Founder of Pendulum Therapeutics, where she focuses on advancing microbiome science and metabolic health through next-generation probiotic research. She holds a PhD in Biochemistry and Molecular Biology from Johns Hopkins University and brings more than 25 years of experience across biotechnology, pharmaceuticals, and academic research.

THANKS TO OUR SPONSOR
Pendulum Therapeutics - http://PendulumLife.com/Kara20
Email: [email protected]

EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS

Using next-generation probiotics like live Akkermansia, Pendulum is designed to go beyond gut health to support metabolism. Visit http://PendulumLife.com/Kara20 and use code KARA20 for 20% off your first membership order.
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Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald speaks with Dr. Robert Lustig about the new USDA dietary guidelines and the broader forces shaping nutrition and metabolic health. Dr. Lustig brings a characteristically direct and nuanced perspective on sugar, ultra-processed foods, and food policy—raising important questions about what drives real change. It’s a thoughtful conversation that challenges assumptions and invites deeper reflection.

Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

GUEST DETAILS
Robert H. Lustig, MD, MSL, is Emeritus Professor of Pediatric Endocrinology at UCSF and a neuroendocrinologist with expertise in obesity, metabolism, and nutrition. Known for his influential work on sugar and ultra-processed foods, Dr. Lustig focuses on improving metabolic health through food system reform, research, and advocacy. He is the author of Fat Chance, The Hacking of the American Mind, and Metabolical, and a leader with Eat REAL, Biolumen, SnapRecall, and Perfact.

Website: https://robertlustig.com/
Email: [email protected]

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DUTCH: https://dutchtest.com/for-providers

Biotics Research: https://www.bioticsresearch.com/

Time—Line Nutrition: https://tinyurl.com/bdzx2xms

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Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. http://mitoq.com/drkara

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Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

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Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

Bone loss doesn’t start when fractures happen — it begins years earlier.

In this episode, we explore how bone aging accelerates during menopause and the emerging role of the gut microbiome as a driver of skeletal decline. Dr. Kara Fitzgerald speaks with research scientists from Sōlaria biō, the company behind Bōndia, about their work studying plant-derived microbes, microbial synergies, and the connections between gut health, inflammation, and bone loss in peri- and postmenopausal women.

We also review findings from a randomized, placebo-controlled clinical trial examining a microbiome-based intervention for bone health — and discuss why bone loss may need to be addressed earlier, systemically, and beyond hormones alone.

Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

GUEST DETAILS

Alicia Ballok, Ph.D. is Director of Discovery at Sōlaria biō, leading research on plant-derived synbiotics for inflammatory and immune-mediated diseases. Trained in Microbiology and Immunology at Dartmouth, with postdoctoral work at Harvard Medical School and Massachusetts General Hospital, her work focuses on translating host–microbe science into therapeutic innovation.

Mark Charbonneau, Ph.D. is Vice President of R&D at Sōlaria biō. He earned his Ph.D. in Computational and Systems Biology at Washington University in St. Louis, studying infant microbiome development and undernutrition. His work spans microbiome research, bioinformatics, and live biotherapeutic innovation.

THANKS TO OUR SPONSOR

Sōlaria biō: http://bit.ly/SolariaBio

EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS

Looking for a clinically proven way to target bone loss? Bōndia by Sōlaria biō is a groundbreaking blend of plant-derived prebiotics and probiotics shown in a clinical trial to improve bone density outcomes by 85%. Try it for yourself at Sōlaria biō and use code Kara20 for 20% off your order.

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Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

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Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw