Each week, Valentin Fuster, MD, PhD, MACC, records free podcasts highlighting journal findings. To keep clinicians updated on the most important science emergin...
In this episode, Dr. Valentin Fuster discusses five key studies from the January 2025 JACC issue, covering advancements in coronary angioplasty, revascularization strategies for STEMI, machine learning for ICD patient outcomes, thromboxane’s link to heart failure, and TAVR valve types and anesthesia approaches. These studies provide valuable insights into improving cardiovascular care and treatment.
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28:06
Drug-Coated Balloon Angioplasty Of the Side Branch During Provisional Stenting: The Multicenter Randomized DCB-BIF Trial
In this episode, Dr. Valentin Fuster discusses the findings of a major randomized trial examining the use of drug-coated balloons (DCB) in treating side branch stenosis during coronary bifurcation procedures. The study suggests that DCBs offer better one-year outcomes compared to non-coated balloons, showing a significant reduction in myocardial infarction rates, but highlights ongoing challenges in managing bifurcation lesions, especially considering the high cost and potential risks.
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10:25
Optimal Strategy for Complete Revascularization in ST-Elevation Myocardial Infarction and Multivessel Disease: A Network Meta-Analysis
In this episode, Dr. Valentin Fuster discusses a comprehensive network meta-analysis published in JACC, which evaluates the optimal strategy for complete revascularization in patients with STEMI and multi-vessel disease. The study concludes that both immediate and staged complete revascularization improve patient outcomes over partial revascularization, with no significant advantage between angiographic and functional guidance, suggesting that angiographic guidance alone may be sufficient in clinical practice.
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10:36
Machine Learning-based Prediction of Death and Hospitalization in Patients with Implantable Cardioverter Defibrillators
In this episode, Dr. Valentin Fuster discusses a groundbreaking study that uses machine learning to predict mortality and hospitalization risks in patients with implantable cardioverter defibrillators (ICDs). By leveraging large datasets and time-varying ICD data, the study developed a robust predictive model, though challenges remain regarding data gaps and its applicability to diverse patient populations.
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11:08
Association of Systemic Thromboxane Generation with Risk of Developing Heart Failure
In this episode, Dr. Valentin Fuster discusses a study published in the Journal of the American College of Cardiology examining the link between urinary thromboxane B2 metabolites and the risk of developing heart failure. The research suggests that high levels of these metabolites, potentially from the myocardium or other organs rather than platelets, are associated with an increased risk of heart failure, offering a potential new biomarker for early detection and targeted prevention strategies.
Each week, Valentin Fuster, MD, PhD, MACC, records free podcasts highlighting journal findings. To keep clinicians updated on the most important science emerging in clinical and translational cardiology, Dr. Fuster provides an overview of the weekly edition from the Journal of the American College of Cardiology (JACC), as well as a short summary of each manuscript. Encompassing JACC and nine cardiovascular specialty journals, the JACC family of journals rank among the top cardiovascular peer-reviewed journals in the world for scientific impact.
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