This Week in Microbiology

• 337: Lifestyles of the Plasmids

  TWiM explains a study that examines pathogen presence in ancient humans and concludes that zoonoses emerged 6500 years ago with the domestication of livestock, and determination of universal rules that govern plasmid copy number. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin Guests: Mark O. Martin Become a patron of TWiM. Links for this episode: Human pathogens in ancient Eurasia (Nature) What once ailed us (NY Times) Rules of plasmid copy number (Nature Comm) Scaling laws of plasmids (Nature Comm) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to [email protected]

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• 336: The Volatilome of Biofluids

  TWiM explores the use of gas sensors and machine learning to identify microbes and antimicrobial resistance in clinical specimens, and how a harmful algal bloom species releases thiamin antivitamins to suppress competitors.   Become a patron of TWiM.   Links for this episode: Microbial and antimicrobial resistance diagnostics (Cell Biomaterials) Thiamin antivitamins suppress algal competitors (mBio) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to [email protected]  

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• 335: Slip Slidin’ Away

  TWiM explains two strategies for bacterial competition for resources: by laying down a slippery lipid and pushing away competitors, or by breaking open cells with a spike, liberating essential nutrients. Become a patron of TWiM. Links for this episode: Secreting a slippery lipid (mBio) Lysing neighboring cells for nutrients (Science) Underwater hockey (YouTube Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to [email protected]

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• 334: Fungal Smuggle

  TWiM describes how microbiological analysis of the Gowanus Canal in Brooklyn has revealed an antimicrobial resistance reservoir and bioremediation potential, and fungicide resistance in Fusarium graminearum, the fungus recently smuggled into the US. Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode Microbiology of the Gowanus Canal (J. Appl. Micro) Microbes clean up Gowanus (BrooklynPaper) Fungicide resistance in Fusarium (Pathogens) Couple smuggles fungal pathogen into US (NBC) Fusarium and wheat-management strategies (Pathogens) Laboratory Biosafety (pdf) NIH Biosafety (NIH) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to [email protected]

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• 333: When Mutualists Murder

  TWiM explains how a mutualistic model bacterium can become lethal in a non-symbiotic host, and engineering a kill switch into a tuberculosis vaccine for improved safety. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode When a mutualist becomes lethal (mBio) A lasting symbiosis (Nat Rev Micro) A kill switch for BCG (Nat Micro) Engineering mycobacteria for vaccination (Nat Micro) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to [email protected]

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