The Evidence Based Rheumatology Podcast

• E129: Long Term Routine Laboratory Monitoring in RA

  Ever wonder how often you really need to check "monitoring" labs? If so then this is the podcast for you! Bryant England mentioned this during his excellent Year in Review session at ACR Convergence 2025. I've been meaning to cover it and finally got around to doing so. Have a listen and share with friends!   Paper: https://pubmed.ncbi.nlm.nih.gov/40854212/

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• E128: Nerandomilast for Autoimmune ILD (FIBRONEER-ILD)

  Covering a very interesting study this week, which investiaged the PDE4B inhibitor nerandomilast for patients with progressive pulmonary fibrosis (specifically including 325 patients with autoimmune ILD). Would have been yet another ho hum trial if not for the big reveal... have a listen to find out! Article: https://www.nejm.org/doi/full/10.1056/NEJMoa2503643  

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• E127: TNFs and All That CHF

  Another episode looking into safety this week! Tackling that pesky issue of TNFs and CHF. Be sure to subscribe to my newsletter and check out the papers below!    Newsletter: https://sprw.io/stt-ee87b4 ATTACH: https://pubmed.ncbi.nlm.nih.gov/12796126/ RENEWAL: https://www.ahajournals.org/doi/10.1161/01.cir.0000124490.27666.b2 Observational Studies: https://pubmed.ncbi.nlm.nih.gov/23155221/  

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• E126: Risk Signals, JAKs, and SELECTIVE-ity

  Covering an interesting but ultimately disappointing post hoc study of multiple upadacitinib trials in RA. Initially some hope for clarity in the "Do JAKs cause all the badness?" questions, but ultimately landing me about where I have been since ORAL-SURVEILLANCE was published Paper: https://www.sciencedirect.com/science/article/pii/S0003496724423091  

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• E125: Adrenal Insufficiency after Stopping Prednisone

  Interesting read this week - I cover a nifty little paper that presented data about adrenal insufficiency after stopping prednisolone, published in JAMA Open in March 2025.     Open Access Journal Here: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831668

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