Optispan is a vision for what health should be.
The typical person gives up 10-20 years of quality life in exchange for disability, frailty, and early death. ...
Epigenetic & Glycan Age Tests Results: Are Biological Age Tests Accurate?
Subscribe to our channel: https://www.youtube.com/@optispan
In this episode of the Optisan Podcast, Dr. George Sutphin discusses biological age tests, focusing on epigenetic and glycan age assessments. The conversation explores the accuracy, relevance, and implications of these tests for understanding biological versus chronological age. Key topics include the limitations of current biomarkers, the impact of lifestyle on aging metrics, and the challenges of interpreting results. The discussion emphasizes the need for caution in marketing claims and the importance of scientific validation in biological age testing.
00:00 - Intro
00:36 - Discussion on biological age tests
04:10 - Defining biomarkers of aging
07:21 - The role of epigenetics in biological aging
10:25 - Skepticism about consumer marketed tests
15:07 - Results from Dr. Sutphin's epigenetic age test
18:51 - Discussion on diet, exercise, and stress
22:30 - Emotional impact of biological age results
26:03 - Summary of organ age results from glycan age test
30:17 - Variability in test results and implications
33:08 - Exploring additional biomarkers for biological age
40:11 - Final thoughts on glycan age and epigenetic clocks
45:21 - Conclusion and takeaways from the discussion
Producers: Tara Mei, Nicholas Arapis
Video Editor: Jacob Keliikoa
DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.
More places to find us:
Twitter: https://twitter.com/optispanpodcast
Twitter: https://twitter.com/optispan
Twitter: https://twitter.com/mkaeberlein
Linkedin: https://www.linkedin.com/company/optispan
Instagram: https://www.instagram.com/optispanpodcast/
TikTok: https://www.tiktok.com/@optispan
https://www.optispan.life/
Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.
On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!
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50:48
Cold Plunge & Brown Fat, Different Types of Stress, and The Power of The Mind | 85
Subscribe to our channel: https://www.youtube.com/@optispan
In this episode with our guest Dr. Thomas Seager, we delve into the transformative power of cold plunge therapy and its profound effects on resilience and longevity. We explore real-life case studies, including lessons learned from infrastructure failures like Hurricane Katrina and the Oroville Dam crisis. Discover how psychological resilience shapes our responses to stress, the importance of hormesis in health, and the role of brown fat in metabolism. We also discuss the impact of fasting, caloric restriction, and the relationship between mitochondrial health and aging.
00:00 - Introduction to Cold Plunge and Resilience
03:33 - Types of Stress & Responses
14:18 - Mitochondrial Health, Caloric Restriction & Metabolism
23:05 - Cold Therapy and Brown Fat
54:10 - Conclusions & Final Thoughts
Producers: Tara Mei, Nicholas Arapis
Video Editor: Jacob Keliikoa
DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.
More places to find us:
Twitter: https://twitter.com/optispanpodcast
Twitter: https://twitter.com/optispan
Twitter: https://twitter.com/mkaeberlein
Linkedin: https://www.linkedin.com/company/optispan
Instagram: https://www.instagram.com/optispanpodcast/
TikTok: https://www.tiktok.com/@optispan
https://www.optispan.life/
Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.
On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!
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1:07:49
Bryan Johnson Stopped Taking THIS & It DOESN'T Make Sense... | 84
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40:03
Doctor of Naturopathy: Microbiome & SIBO, Platelet-Rich Plasma Therapy, BPC-157, Dieting Advice | 83
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1:00:28
I Took 4 Different Biological Age Tests & Compared the Results... | 82
Subscribe to our channel: https://www.youtube.com/@optispan
Related Episode(s):Biological Age & what it REALLY means | 9 - Longevity Science #3: https://youtu.be/DcxgEwQKx8Q?si=y1iF4RviJc0n__gW
In this deep dive, Matt examines the growing trend of direct-to-consumer biological (epigenetic) age testing kits, exploring their purpose, popularity, and limitations. He outlines his experimental design to evaluate the accuracy and precision of these tests, addressing important questions about what they truly measure and how reliable they are. Matt unpacks the difference between biological and chronological age, discusses the co-marketing strategies employed by these companies, and reflects on his own results to provide a critical perspective on the value of these kits.
0:00 Introduction
2:17 Experimental Design
3:03 Key Questions
5:15 Marketing Strategies of Bio-Age Companies
6:15 Biological Age vs. Chronological Age
6:49 Measuring Biological Age
8:32 Limitations of Epigenetic Clocks
13:23 Accuracy and Precision
15:49 Data Analysis
19:22 Matt’s Biological Age Results
22:53 Key Takeaways
24:50 Sanity Checks
31:58 Conclusions
Producers: Tara Mei, Nicholas Arapis
Video Editor: Jacob Keliikoa
DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.
More places to find us:
Twitter: https://twitter.com/optispanpodcast
Twitter: https://twitter.com/optispan
Twitter: https://twitter.com/mkaeberlein
Linkedin: https://www.linkedin.com/company/optispan
Instagram: https://www.instagram.com/optispanpodcast/
TikTok: https://www.tiktok.com/@optispan
https://www.optispan.life/
Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.
On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!
Acerca de The Optispan Podcast with Matt Kaeberlein
Optispan is a vision for what health should be.
The typical person gives up 10-20 years of quality life in exchange for disability, frailty, and early death. We call this "the lost decade". Time that should be spent with loved ones doing the activities you enjoy are instead spent suffering from multiple diseases and taking a cabinet full of medications that probably do as much harm as good.
We believe that the current practice of medicine is disease care, not health care. We believe that everyone can get closer to their own optimal healthspan.