Ninja Nerd

• Antiplatelets, Anticoagulants, and Thrombolytics

  Ninja Nerds!Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Antiplatelets, Anticoagulants, and Thrombolytics, focusing on their mechanisms and clinical uses. Topics include the pharmacology of antiplatelet agents such as aspirin and P2Y12 inhibitors, the role of anticoagulants like heparins, direct oral anticoagulants (DOACs), and warfarin in preventing thromboembolic events, and the use of thrombolytics like tPA in acute ischemic stroke and myocardial infarction. We also discuss strategies for managing bleeding risks, reversal agents, and clinical considerations for optimizing anticoagulation therapy. Enjoy the episode, and support us below!Support the show

  --------  

  47:19
• Hypercoagulable States

  Ninja Nerds!Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Hypercoagulable States, covering key disorders and their clinical significance. Topics include Antiphospholipid Syndrome (APLS), its role in thrombosis and pregnancy loss; Factor V Leiden Mutation, the most common inherited thrombophilia; and Prothrombin Gene Mutation and its increased clotting risk. We also explore Protein C and S Deficiency, Antithrombin Deficiency, and acquired states like Cancer-Associated Thrombosis, Heparin-Induced Thrombocytopenia (HIT), and Paroxysmal Nocturnal Hemoglobinuria (PNH). Tune in to learn more, and support us below!Support the show

  --------  

  39:33
• Coagulopathy

  Ninja Nerds!Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Coagulopathy, focusing on key bleeding and clotting disorders. Topics include Hemophilia A and B, their genetic causes, and modern treatments; Von Willebrand Disease (vWD), the most common inherited bleeding disorder; and Heparin-Induced Coagulopathy, with its paradoxical effects. We also cover Acquired Factor VIII Inhibitors in autoimmune and malignancy settings, Vitamin K Deficiency as a cause of bleeding, Disseminated Intravascular Coagulation (DIC) and its management challenges, and coagulopathy in Cirrhosis, linking liver dysfunction to bleeding and thrombosis. Enjoy the episode, and support us below!Support the show

  --------  

  39:33
• Platelet Disorders

  Ninja Nerds!Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Platelet Disorders, breaking down the essential concepts and clinical applications. We will discuss Heparin-Induced Thrombocytopenia (HIT), focusing on its pathophysiology and management. Learn about Antiphospholipid Syndrome (APLS) and its role in thrombosis and pregnancy complications. We’ll also cover Disseminated Intravascular Coagulation (DIC), including its triggers and treatment strategies, and Hemolytic Uremic Syndrome (HUS), with an emphasis on its pediatric presentations. Dive into Thrombotic Thrombocytopenic Purpura (TTP) and its life-threatening manifestations, Von Willebrand Disease (vWD) as the most common inherited bleeding disorder, and Immune Thrombocytopenic Purpura (ITP), highlighting its diagnostic approach and treatment. Enjoy the podcast, and please support us below!Support the show

  --------  

  58:22
• Blood Transfusions

  Ninja Nerds!Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we dive into blood transfusions, breaking down the essential components and clinical uses. We will discuss packed red blood cell transfusions (PRBC) for anemia management, platelet transfusions for thrombocytopenia and bleeding risk, and the role of Fresh Frozen Plasma (FFP) transfusions in reversing anticoagulation or treating coagulopathies. You will also learn about Prothrombin Complex Concentrate (PCC) transfusions for rapid anticoagulant reversal, Cryoprecipitate Transfusions for fibrinogen replacement, and how to manage complications like transfusion-related acute lung injury (TRALI). Lastly, we will tackle the massive transfusion protocol (MTP), also known as a Code Crimson, highlighting its life-saving importance in critical care settings. Enjoy the podcast, and please support us below!Support the show

  --------  

  1:00:31

Más podcasts de Salud y forma física

Podcasts a la moda de Salud y forma física

Acerca de Ninja Nerd