ICU Ed and Todd-Cast

• ISICEM Review and SESAR

  Send us a Text Message (please include your email so we can respond!)Episode 62! We talk briefly about two of the analyses that dropped with the ISICEM conference and then talk in depth about SESAR or "Inhaled Sedation in Acute Respiratory Distress Syndrome" by Jabudon et al in JAMA 2025. Then was answer a question on sleep in the ICU. Eddie did misspeak when he said one of the dexmedetomidine articles was in Lancet Respiratory medicine, rather, it was published in eClinical Medicine part of the Lancet network.SESAR (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2831857SESAR (pubmed): https://pubmed.ncbi.nlm.nih.gov/40098564/OVISS (pubmed): https://pubmed.ncbi.nlm.nih.gov/40098600/Nocturnal dexmedetomidine (pubmed): https://pubmed.ncbi.nlm.nih.gov/29498534/Nocturnal dexmedetomidine cardiac surgery (pubmed): https://pubmed.ncbi.nlm.nih.gov/36590787/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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• New/Review: Extubating to HFNC

  Send us a Text Message (please include your email so we can respond!)Episode 61! We talk about HFNC including extubation to HFNC in "Early weaning from invasive mechanical ventilation via high-flow nasal oxygen versus conventional weaning in patients with hypoxemic respiratory failure" by Ayyawar et al published in Critical Care Science. Then we talk about weaning HFNC from the "How I do it" series from CHEST.Auto-PEEP (NEJM): https://www.nejm.org/doi/full/10.1056/NEJM199307153290322Extubate to HFNC (pubmed): https://pubmed.ncbi.nlm.nih.gov/39879434/Extubate to HFNC (CCS): https://criticalcarescience.org/article/early-weaning-from-invasive-mechanical-ventilation-via-high-flow-nasal-oxygen-versus-conventional-weaning-in-patients-with-hypoxemic-respiratory-failure-a-prospective-randomized-controlled-study/Weaning HFNC (pubmed): https://pubmed.ncbi.nlm.nih.gov/39929280/Weaning HFNC (CHEST): https://journal.chestnet.org/article/S0012-3692(25)00155-2/abstractIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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• SCCM: PROACTIVE and ASA in sepsis

  Send us a Text Message (please include your email so we can respond!)Episode 60! We jump to SCCM where we talk about 2 late breakers - PROACTIVE or "Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation" by Downar et al and "Acetylsalicylic Acid Treatment in Patients With Sepsis and Septic Shock" by Almeida et al both published in CCM in 2025. PROACTIVE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39982178/PROACTIVE (CCM): https://pmc.ncbi.nlm.nih.gov/articles/PMC11801419/ASA in sepsis (pubmed): https://pubmed.ncbi.nlm.nih.gov/39982179/ASA in sepsis (CCM): https://journals.lww.com/ccmjournal/fulltext/2025/02000/acetylsalicylic_acid_treatment_in_patients_with.2.aspxIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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• TRAUMOX2, SAHARA, and mailbag

  Send us a Text Message (please include your email so we can respond!)Episode 59! We finish our CCR down under coverage with TRAUMOX2 or "Early Restrictive vs Liberal Oxygen for Trauma Patients" published in JAMA by Arleth et al and then switch to SAHARA or "Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage" by English et al published in NEJM. We then frustrate Todd with questions from our mailbag, a good episode!TRAUMOX2 (pubmed): https://pubmed.ncbi.nlm.nih.gov/39657224/TRAUMOX2 (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2827980SAHARA (pubmed): https://pubmed.ncbi.nlm.nih.gov/39655786/SAHARA (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2410962If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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• Old/New: FLORALI and RENOVATE

  Send us a Text Message (please include your email so we can respond!)Episode 58! We talk about non-invasive oxygen support and RENOVATE or "High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure" published in JAMA December 2024 and presented at the CCR Down Under Conference. We supplement this by first talking about FLORALI or "High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure" published in NEJM May 2015RENOVATE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39657981/RENOVATE (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2828065FLORALI (pubmed): https://pubmed.ncbi.nlm.nih.gov/25981908/FLORALI (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa1503326If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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