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The Infectious Science Podcast

Galveston National Laboratory
The Infectious Science Podcast
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  • War & Pathogens, How Combat Drives Contagion
    Send us a textWar is a vector of disease. The battlefield isn't just a place where bullets fly—it's where pathogens thrive and evolve. Throughout human history, war and disease have been inseparable companions, creating perfect storms of contagion that affect soldiers and civilians alike.Our journey begins in the Boer War concentration camps where measles swept through malnourished populations. We explore how the densely packed, unsanitary conditions created an environment where this highly contagious virus could spread with unprecedented severity, even among adults who typically have greater resistance.The trenches of World War I became breeding grounds for tuberculosis—a disease that claimed millions of lives with no effective treatment available beyond isolation, nutrition, and exposure to fresh air and sunlight. It would be decades after the war ended before the first effective medications were developed in the 1940s.War doesn't just spread existing diseases—it creates conditions for new ones to emerge. During World War II, when farming ceased in the occupied Crimean Peninsula, overgrown grasslands became habitats for wildlife and the ticks they carried. When Russian soldiers reclaimed the area in 1944, they encountered what would later be identified as Crimean-Congo hemorrhagic fever. Similarly, the Korean War saw the emergence of Hantavirus among US soldiers.Perhaps most alarming is our exploration of the current Russia-Ukraine conflict, where overstretched medical systems have accelerated antimicrobial resistance to frightening levels. Klebsiella pneumoniae from Ukrainian wounds exhibits carbapenem resistance rates ten times higher than those observed anywhere else in Europe. These resistant strains are already crossing borders, detected in six European countries and as far away as Japan.The displacement of populations, collapse of healthcare infrastructure, and ecological disruptions caused by conflict create ripple effects that extend far beyond the battlefield. As one expert reminds us, perhaps "more effective than any vaccine, is peace."Subscribe, share, and join us next time as we continue exploring the intricate connections between human activity and disease emergence. The more we understand these relationships, the better prepared we'll be to face future health challenges.Thanks for listening to the Infectious Science Podcast. Be sure to visit infectiousscience.org to join the conversation, access the show notes, and don’t forget to sign up for our newsletter to receive our free materials. We hope you enjoyed this new episode of Infectious Science, and if you did, please leave us a review on Apple Podcasts and Spotify. Please share this episode with others who may be interested in this topic! Also, please don’t hesitate to ask questions or tell us which topics you want us to cover in future episodes. To get in touch, drop us a line in the comment section or send us a message on social media. Instagram @InfectscipodFacebook Infectious Science PodcastSee you next time for a new episode!
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  • Beyond the Sequence: People, Pathogens, and Power Dynamics
    Send us a textThe cutting edge of infectious disease control isn't just about vaccines or treatments—it's increasingly about data. Dr. Stephen Molldrem, Assistant Professor at the Institute for Bioethics and Health Humanities, takes us deep into the world of pathogen genomics and the remarkable ethical questions that emerge when we sequence disease-causing microorganisms.What happens when genetic analysis can potentially reveal who infected whom with HIV? Why do some communities welcome these technologies while others resist them? From the controversies surrounding HIV surveillance in America to the enthusiastic adoption of TB genomics in Botswana, Dr. Molldrem reveals how the same scientific tools can take on dramatically different meanings depending on context, trust, and community involvement.The COVID-19 pandemic accelerated the global adoption of pathogen sequencing, bringing terms like "variants" and "mutations" into everyday conversation. But this technological revolution has also revealed deep inequities—when South African scientists identified the Omicron variant and transparently shared this information, their reward was travel bans rather than support. This pattern reveals how scientific advancement doesn't happen in a vacuum but within complex social and political realities.At the heart of Dr. Molldrem's work is a fundamental reminder: behind every genetic sequence is a person, a community, and a set of lived experiences. As one HIV advocacy slogan puts it, "We are people, not clusters." The challenge for public health isn't just implementing new technologies but doing so in ways that respect human dignity and build rather than undermine trust.Whether you're fascinated by the science of disease tracking, concerned about health privacy, or interested in how new technologies reshape our understanding of outbreaks, this episode offers a thought-provoking journey through the socio-technical landscape of modern infectious disease control. Join us as we explore what happens when cutting-edge science meets complex human realities.Thanks for listening to the Infectious Science Podcast. Be sure to visit infectiousscience.org to join the conversation, access the show notes, and don’t forget to sign up for our newsletter to receive our free materials. We hope you enjoyed this new episode of Infectious Science, and if you did, please leave us a review on Apple Podcasts and Spotify. Please share this episode with others who may be interested in this topic! Also, please don’t hesitate to ask questions or tell us which topics you want us to cover in future episodes. To get in touch, drop us a line in the comment section or send us a message on social media. Instagram @InfectscipodFacebook Infectious Science PodcastSee you next time for a new episode!
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  • From Four Corners to Hollywood: Tracing Hantavirus's Deadly Path
    Send us a textA hidden killer lurks in the humble dust of forgotten cabins and outbuildings across America. World-renowned virologist Dr. Thomas Ksiazek takes us behind the scenes of the landmark 1993 Four Corners outbreak, where hantavirus first emerged on the national stage, claiming lives with a swift and devastating pulmonary syndrome unlike anything seen before in North America.With over four decades on the frontlines of viral discovery and outbreak response, Dr. Ksiazek shares the detective story of how his team at the CDC identified Sin Nombre ("no name") virus by drawing on their unique expertise with Asian hantaviruses. He explains the ecological cascade that triggers cyclical rodent population explosions, creating perfect conditions for spillover into human communities.The conversation turns chillingly relevant as we discuss recent high-profile cases, including the tragic February 2024 death of Betsy Arakawa Hackman, and a cluster of deaths in Mammoth Lakes, California. Dr. Ksiazek explains why spring cleaning poses a particular risk when disturbing rodent-contaminated areas, and why conventional treatments often prove ineffective against the rapid progression of hantavirus pulmonary syndrome.As both a co-discoverer of the original SARS coronavirus and a veteran of countless global outbreaks, Dr. Ksiazek offers profound wisdom on what makes outbreak responses succeed or fail. His insights on the critical importance of early detection and international cooperation carry urgent lessons for our pandemic-weary world. Whether you're a scientist, healthcare worker, or simply someone who might one day clean out a dusty cabin, this episode delivers potentially life-saving knowledge about a persistent threat hiding in plain sight.Thanks for listening to the Infectious Science Podcast. Be sure to visit infectiousscience.org to join the conversation, access the show notes, and don’t forget to sign up for our newsletter to receive our free materials. We hope you enjoyed this new episode of Infectious Science, and if you did, please leave us a review on Apple Podcasts and Spotify. Please share this episode with others who may be interested in this topic! Also, please don’t hesitate to ask questions or tell us which topics you want us to cover in future episodes. To get in touch, drop us a line in the comment section or send us a message on social media. Instagram @InfectscipodFacebook Infectious Science PodcastSee you next time for a new episode!
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  • Measles: The Return of a Highly Contagious Disease
    Send us a textMeasles isn't just a childhood rash—it's a potentially devastating illness that can reset your entire immune system. In this eye-opening conversation, our team explores why this ancient virus still demands our attention in 2025.When we began recording this episode, a troubling measles outbreak was unfolding in Texas, with two unvaccinated children already having lost their lives. We dive into the history of this disease, tracing its evolution from cattle plague to human pathogen and explaining why the World Health Organization classifies it as one of the world's most contagious diseases.What makes measles particularly dangerous isn't just its extraordinary transmissibility—it's a phenomenon called "immune amnesia." This lesser-known complication can erase your body's hard-earned immunity to other pathogens for up to three years after infection. Dr. Matt Dasco shares his firsthand clinical experiences treating measles patients, painting a vivid picture of why prevention is so crucial.The good news? We have an exceptionally effective vaccine. The MMR (measles, mumps, rubella) vaccine provides 97% protection after two doses and confers lifetime immunity. Yet despite this medical marvel, vaccine hesitancy fueled by misinformation has allowed measles to stage a comeback after being declared eliminated in the US in 2000.Our team doesn't shy away from addressing difficult questions about vaccine communication, acknowledging that building trust requires honest conversations about both benefits and risks. We explore why middle and high-income communities often experience higher vaccine hesitancy and how social media amplifies misinformation.Whether you're concerned about current outbreaks, curious about infectious disease, or simply want to understand how to evaluate health information critically, this episode offers vital insights into protecting our communities from a preventable threat. Subscribe now to join our evidence-based conversation about the health challenges that affect us all.Thanks for listening to the Infectious Science Podcast. Be sure to visit infectiousscience.org to join the conversation, access the show notes, and don’t forget to sign up for our newsletter to receive our free materials. We hope you enjoyed this new episode of Infectious Science, and if you did, please leave us a review on Apple Podcasts and Spotify. Please share this episode with others who may be interested in this topic! Also, please don’t hesitate to ask questions or tell us which topics you want us to cover in future episodes. To get in touch, drop us a line in the comment section or send us a message on social media. Instagram @InfectscipodFacebook Infectious Science PodcastSee you next time for a new episode!
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  • Googling the Flu: How Your Search History Became a Public Health Tool
    Send us a textWhat if your Google searches could predict disease outbreaks before traditional surveillance methods? That's exactly what happened during the 2009 H1N1 pandemic when researchers discovered online search patterns matched CDC data – but delivered results much faster.Welcome to the fascinating world of infodemiology, where digital footprints become powerful tools for public health. In this eye-opening conversation with experts Dr. Heather Duncan and Dr. Patrick Murphy, we explore how researchers analyze everything from tweets to search queries to understand health trends, track disease spread, and even identify mental health risks.The implications are both promising and concerning. While infodemiology offers unprecedented speed and insights for public health response, it raises critical questions about privacy, ethics, and the responsibility that comes with identifying health risks online. If AI flags someone as potentially suicidal based on their social media activity, what obligations exist to connect them with resources?Perhaps most shocking is the revelation that just 12 individuals were responsible for 60% of the anti-vaccine content circulating on certain platforms. This precision mapping of information flow demonstrates infodemiology's potential to target interventions effectively.As social media increasingly becomes Americans' primary source of health information, understanding these digital dynamics becomes crucial for public health. Dr. Duncan shares her vision of creating accessible, automated tools that would allow even small health departments to harness these powerful insights without extensive resources.Subscribe to Infectious Science for more fascinating conversations at the intersection of technology and public health, and share your thoughts on how digital surveillance might shape the future of healthcare.Thanks for listening to the Infectious Science Podcast. Be sure to visit infectiousscience.org to join the conversation, access the show notes, and don’t forget to sign up for our newsletter to receive our free materials. We hope you enjoyed this new episode of Infectious Science, and if you did, please leave us a review on Apple Podcasts and Spotify. Please share this episode with others who may be interested in this topic! Also, please don’t hesitate to ask questions or tell us which topics you want us to cover in future episodes. To get in touch, drop us a line in the comment section or send us a message on social media. Instagram @InfectscipodFacebook Infectious Science PodcastSee you next time for a new episode!
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🌍 Welcome to the Infectious Science Podcast – Your source for cutting-edge insights on infectious diseases and the power of the One Health approach! 🎙️Our mission? To empower YOU with the knowledge to better understand and prevent the spread of emerging diseases. Whether you're a researcher, clinician, student, or simply curious about public health, we bring experts and thought leaders together to spark innovation, collaboration, and critical thinking.Join us as we dive into the latest research, share inspiring stories, and make complex science accessible to everyone. Let’s build a healthier, more resilient world—one episode at a time! 🌱💡Subscribe now and become part of the global community driving a safer future! #OneHealth #PublicHealth #InfectiousDiseases
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