Psychopharmacology and Psychiatry Updates

In this episode, we explore KarXT, a newly FDA-approved antipsychotic with a groundbreaking cholinergic mechanism, through the lens of a single powerful metric: the Number Needed to Treat. Could an NNT of 5 change how you approach treatment-resistant schizophrenia?
Faculty: Oliver Freudenreich, M.D.
Host: Richard Seeber, M.D.
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Earn 0.75 CMEs: Quick Take Vol. 80
How Effective Is KarXT (Xanomeline-Trospium) for Schizophrenia? NNT and NNH Explained

In this episode, we explore how to keep your patients on lithium by getting ahead of two of its most common challenges — weight gain and gastrointestinal side effects. Dr. David Osser from Harvard Medical School shares practical, proactive strategies to anticipate, prevent, and manage these issues before they drive your patients away from a medication that could truly change their lives.
Faculty: David Osser, M.D.
Host: Richard Seeber, M.D.
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Earn 1.5 CME: Lithium: How to Manage Dosage and Side Effects
How to Mitigate Weight Gain and Gastrointestinal Side Effects of Lithium

In this episode, we explore a surprising new contender in the fight against alcohol use disorder — semaglutide. Could the blockbuster weight-loss drug also curb heavy drinking? We examine the first randomized controlled trial testing this GLP-1 receptor agonist specifically for AUD.
Faculty: David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M.
Host: Richard Seeber, M.D.
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Earn 0.75 CMEs: Quick Take Vol. 79
Semaglutide for Alcohol Use Disorder: New RCT Data

In this episode, we explore lithium's renal side effects with Dr. David Osser from Harvard Medical School. How can we keep patients safe while using this highly effective medication? Discover the real risk numbers, prevention strategies, and evidence-based monitoring approaches that protect kidney function long-term.
Faculty: David Osser, M.D.
Host: Richard Seeber, M.D.
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Earn 1.5 CMEs: Lithium: How to Manage Dosage and Side Effects
Managing Renal Side Effects of Lithium Therapy

In this episode, we explore cariprazine's efficacy and safety in older adults with bipolar I disorder. Does age change how we should dose this medication? Discover evidence-based insights on treating both depression and mania in elderly patients, plus critical pearls on monitoring for akathisia.
Faculty: Kristin Raj, M.D.
Host: Richard Seeber, M.D.
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Earn 0.75 CMEs: Quick Take Vol. 79
Cariprazine Dosing for Bipolar Disorder In Older Adults