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The Metabolic Link

Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field
The Metabolic Link
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  • Can a Ketogenic Diet Improve Sleep Apnea? | Dr. Jonathan Jun | The Metabolic Link Ep. 78.
    What if the food you eat could change the way you breathe at night? In this episode, recorded live at The Metabolic Health Summit, Dr. Jonathan Jun reveals how metabolism and sleep-disordered breathing are deeply connected, and why shifting from carbs to fat might improve more than just your waistline.Dr. Jonathan Jun, a leading researcher on obesity hypoventilation syndrome (OHS) and obstructive sleep apnea (OSA), walks us through the groundbreaking KETOHS trial, where a ketogenic diet was tested for its effects on carbon dioxide retention, sleep apnea severity, and metabolic health. The findings suggest ketosis may do more than promote weight loss - it could directly enhance respiratory efficiency and sleep quality in patients with OHS and OSA.From a long-forgotten 1976 fasting study to modern clinical data, this lecture reframes the connection between diet, breathing, and metabolism, revealing how nutritional ketosis might transform respiratory and metabolic medicine.Questions Answered in This Episode:Why does fuel choice (carbs vs. fat) matter for breathing in people with sleep-disordered breathing?What exactly happens in obesity hypoventilation syndrome (OHS), and why is it more dangerous than OSA alone?Why did a 1976 starvation ketosis study inspire modern trials on ketogenic diets for OSA/OHS?How was the KETOHS trial designed to isolate the effects of ketosis itself (not just weight loss)?Can a ketogenic diet improve sleep apnea severity even without CPAP therapy?Is the improvement in CO₂ clearance explained only by weight loss, or something else?What metabolic changes accompany ketogenic therapy in this context?This episode will change the way you see the link between diet and breathing, and may open new doors for treating some of the toughest sleep and metabolic disorders.Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here. ✅ ZocDoc - Find and instantly book a top-rated doctor here.✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
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  • The Metabolic Approach to Treating Food Addiction | Dr. Tro Kalayjian | The Metabolic Link Ep. 77
    Could treating food like a drug be the breakthrough we've needed in food addiction treatment?In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Tro Kalayjian - physician, researcher, and former obesity patient - to explore whether food addiction should be classified as a true addiction, and how his TOWARD model is helping patients overcome binge eating and food-related compulsions.Dr. Tro shares findings from his recent peer-reviewed paper, TOWARD: a Metabolic Health Intervention That Improves Food Addiction and Binge Eating Symptoms. The study evaluated outcomes from the TOWARD intervention, a telemedicine-based model that combines metabolic nutrition, real-time biofeedback, and coaching. Nearly half of participants reduced food addiction symptoms, and over 80% saw improvements in binge eating - often independent of weight loss.This conversation explores the science of dopamine signaling, the failure of calorie-restriction models, the blurred line between food addiction and eating disorders, and how this approach could reshape treatment through scalable, real-world solutions.Questions Answered in This Episode:How should we define food addiction compared to binge eating disorder?Should ultra-processed food addiction be officially recognized in the DSM?Why is food addiction harder to treat than drug or alcohol addiction?What were the key outcomes of the TOWARD study on food addiction and binge eating?Can lifestyle interventions compete with bariatric surgery or GLP-1 drugs?How can employers scale food addiction treatment for high-risk populations?Check out Dr. Kalajian's TOWARD app here.Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here!✅Cowboy Colostrum - Get 25% offwhen you use code METABOLICLINK at checkout!✅Piquelife.com - Get the Pu'er Bundle for 20% off here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
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  • Built to Last: Muscle, Longevity, and Training Smarter | Dr. Andy Galpin | The Metabolic Link Ep. 76
    Muscle isn’t just about strength or performance — it’s metabolic armor. In this episode of The Metabolic Link, Dr. Andy Galpin sits down with hosts Victoria Field and Dr. Dominic D’Agostino to show how muscle, cardio fitness, and bone density work together to protect against decline and extend healthspan. From women’s training and recovery practices to kids in the weight room, Dr. Galpin translates decades of research into practical strategies anyone can use.Big questions Dr. Galpin helps answer:How does muscle mass protect against metabolic decline and early mortality?What’s the safest, most effective on-ramp to rebuild bone density and explosiveness after 40?When is fasted training useful for women, and when is it counterproductive?How early can kids start resistance training — and what should it look like?Which recovery practices are underrated (free) versus overrated (pricey)?Dr. Andy Galpin is a tenured full professor and human performance scientist with a PhD in Human Bioenergetics and an MS in Human Movement Sciences. He previously ran the Center for Sport Performance and the Biochemistry & Molecular Exercise Physiology Lab at Cal State Fullerton, and now serves as Executive Director of the Human Performance Center at Parker University. He has authored over 50 peer-reviewed publications, coaches elite athletes across the UFC, NBA, MLB, NFL, Olympics, and special forces, and is the host of the Perform with Dr. Andy Galpin podcast, where he shares insights from two decades of working with world-class performers.Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here!✅ Branch Basics - Get 15% off your Premium Starter Kit here✅ iRestore - Get a huge discount on the iRestore Illumina Face Mask when you use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
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  • Redefining Recovery: A Metabolic Approach to Plastic Surgery | Cameron Chesnut, MD | The Metabolic Link Ep.75
    Plastic surgery meets metabolic medicine.Dr. Cameron Chesnut isn't just changing faces - he's changing the entire surgical process. In this episode, Dr. Dominic D'Agostino talks with the facial plastic surgeon who’s using ketones, hyperbaric oxygen, red light, and regenerative protocols to optimize brain health, accelerate recovery, and eliminate opioids entirely.Trusted by high performers around the world, Dr. Chesnut is known for delivering natural, rejuvenated, and seemingly untouched results through minimally invasive procedures. His practice integrates regenerative medicine, metabolic science, and next-level recovery techniques — all grounded in a personal performance protocol as refined as his surgical outcomes.In this episode, he and Dr. Dominic D’Agostino unpack the future of surgical care: ketones for cognitive protection, hyperbaric oxygen for faster healing, red light and PEMF for recovery, and the anesthesia protocols he uses to avoid post-op brain fog — and eliminate opioids altogether.This isn’t cosmetic — it’s clinical strategy. And it could change the face of plastic surgery as we know it.Where to find Dr. Chesnut online:InstagramAboutStart Your Journey Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here.✅ ZocDoc - Find and instantly book a top-rated doctor here.✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
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  • Reversing Alzheimer's Disease | Dr. Dale Bredesen | The Metabolic Link Ep.74
    Did you know that over 7 million Americans live with Alzheimer’s—and that number is expected to nearly double by 2050? Despite decades of research and billions spent, most treatments only offer minimal slowing of symptoms.But what if we’ve been approaching this disease all wrong?In this powerful episode of The Metabolic Link, host Victoria Field sits down with renowned neurologist, researcher, and bestselling author Dr. Dale Bredesen. He shares how Alzheimer’s isn’t caused by one thing—and why he says a single-pill solution is a fundamentally flawed approach. Dr. Bredesen discusses his 30+ years of research into cognitive decline, the systems-based ReCODE Protocol that’s showing incredible success in reversing symptoms, and why early detection is everything.From brain biomarkers to root causes like inflammation, toxins, and metabolic dysfunction, this is a masterclass on how we can take action—long before symptoms take hold.🎯 Plus: In honor of World Alzheimer's Month, we're hosting a Live Q&A with Dr. Bredesen on Sept 4th at 9AM PT/12PM ET — FREE with a 7-day trial of our medical education platform, the Metabolic Initiative. Sign up: https://membership.metabolicinitiative.com/bredesenSpecial thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here!✅ Branch Basics - Get 15% off your Premium Starter Kit here✅ iRestore - Get a huge discount on the iRestore Illumina Face Mask when you use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
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Welcome to The Metabolic Link, a medical and science podcast that explores the common thread of metabolism in health and disease. Join Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field as they dive into the latest research on metabolic health and therapy alongside some of the world’s leading experts. They'll also discuss how this science is being applied in the real world. This is where science meets society.
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