Ep. 303: “Organoid Models of Cancer” Featuring Dr. Alice Soragni
Dr. Alice Soragni is an Associate Professor at the University of California, Los Angeles. She talks about her work on patient-derived organoids and how they can be adapted for drug screening. She also discusses how she transitioned from structural biology to research on protein aggregation and rare diseases, and the current social media landscape for scientists.
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Ep. 302: “Kidney Organoids” Featuring Dr. Zhongwei Li
Dr. Zhongwei Li is an Associate Professor at the University of Southern California. His lab focuses on kidney organogenesis with translational applications of kidney regeneration and disease modeling. He talks about his work on PSC-derived nephron progenitors and drug discovery applications for polycystic kidney disease.
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1:18:39
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Ep. 301: “Cell Fate Decisions in Cancer” Featuring Dr. Mark Hatley
Dr. Mark Hatley is an Associate Faculty Member and Director of the Division of Molecular Oncology at St. Jude Children's Research Hospital. His research focuses on the developmental origins and genetic mechanisms of pediatric rhabdomyosarcoma. He talks about his work on pediatric oncology and the mechanisms that differentiate normal development from cancer. He also discusses the role of PAX3-FOXO1 and DICER1 in tumorigenesis.
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Ep. 300: “Autologous Cell Therapy” Featuring Dr. Jeanne Loring
Dr. Jeanne Loring is a Co-Founder of Aspen Neuroscience and Professor Emeritus at Scripps Research. She talks about generating gametes from the functionally extinct northern white rhinoceros, Aspen's early days and its recent clinical trial results for Parkinson's cell therapy, and sending her own stem cells into space. She also discusses the need for genetic variation in iPSC lines.
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Ep. 299: “Spinal Cord Development” Featuring Dr. James Briscoe
Dr. James Briscoe is a Group Leader at the Francis Crick Institute and Editor-In-Chief of Development. His lab uses an interdisciplinary approach, including mice, chicks, and other models, to study developmental dynamics. He discusses his lab's work on human trunk formation and his role as an Editor-In-Chief.
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